SkinCeuticals P-TIOX Serum

A targeted wrinkle-smoothing serum built around a high-concentration neuropeptide complex that interrupts the muscle contraction signals responsible for expression lines on the forehead, between the brows, and around the eyes.

P-TIOX delivers a 10% blend of three peptides (acetyl hexapeptide-8, acetyl heptapeptide-1, and dipeptide diaminobutyroyl benzylamide diacetate) that target the SNARE complex involved in releasing acetylcholine at the neuromuscular junction. In clinical evaluation, the formula has shown measurable reductions in dynamic wrinkle depth after four weeks of twice-daily use. The serum has a silky, fast-absorbing texture that layers well under sunscreen and makeup.

Apply 4 to 5 drops to clean skin morning and evening. Press into areas where expression lines form (forehead, between the brows, crow's feet, and the upper lip). Follow with moisturizer and SPF during the day. Best results visible after 8 to 12 weeks of consistent use.

Visible dynamic wrinkles (lines that appear with facial movement); patients between neuromodulator appointments who want to extend results; anyone who prefers topical alternatives to injectables.

Shipping. Orders ship from Vancouver, BC via Canada Post Express with tracking on every order. Complimentary express shipping on orders over $150 CAD. Orders to the United States are shown in USD at checkout, where any duties or taxes are calculated.

Returns. Unopened, sealed items may be returned within 14 days of delivery. For health and hygiene reasons, opened skincare is final sale and cannot be returned, except where it arrived damaged, defective, or was shipped in error.

Costs. We charge no restocking fees. Standard return shipping is the customer's responsibility; we provide a prepaid label for damaged, defective, or wrong-item returns. If a return brings a free-shipping order below the $150 threshold, the original outbound shipping may be deducted from the refund.

Damaged on arrival? Email info@curatedclinicals.com with photos within 48 hours of delivery and we will make it right. Approved refunds are issued to your original payment method within 5 to 10 business days of us receiving the return.

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